I Built a 592-Entry Herb-Drug Interaction Database — Here's What the Data Reveals

Last year I started building a free herb-drug interaction checker for Spanish-speaking users in Latin America. What began as a simple lookup table turned into a 592-entry database with severity classifications and PubMed citations. Here's what the data looks like — and what surprised me. The Database 592 interactions between 204 medicinal herbs and pharmaceutical drugs, each classified by severity: Severity Count % What it means Alta (High) 84 14.2% Potentially life-threatening. Avoid combination. Moderada (Moderate) 288 48.6% Clinically significant. Monitor closely. Baja (Low) 220 37.2% Minor effect. Usually safe with awareness. Every entry includes a mechanism of action and links to published evidence. No "trust me bro" — actual pharmacological reasoning. The Dangerous Herbs (by interaction count) Some herbs interact with everything . Here are the top 10 by number of known drug interactions: Hypericum (St. John's Wort) → 26 interactions Curcuma (Turmeric) → 16 interactions Ginkgo bil